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Siena Biotech S.p.A. Chooses Provantis to Support In Vivo Activities in Bioanalytical Department

Provantis™ Selected to Structure Workflow, Support Efficiency and Reduce Costs

CONSHOHOCKEN, PA - March 21, 2007 - Instem, a premier global information solutions provider, announced today that Siena Biotech S.p.A. ("Siena") has chosen Provantis to structure the flow of their in vivo bioanalytical data in Siena, Italy.

Instem's Provantis solution will be used to communicate with Siena's bioanalytical applications and equipment through software developed by Instem's experienced instrument interfacing team.

"It was after visiting an Instem customer site, as part of our evaluation process, that we chose Provantis as the application to support our in vivo activities," commented Dr. Goran Westerberg, Head of Drug Profiling, Siena Biotech S.p.A. "Instem's focus and their support services will contribute to our operational success and add value to our activities as a drug discovery company."

"Using Provantis to interface with their bioanalytical operations is an effective way to leverage our software to help them manage and integrate bioanalytical output in a convenient and protected environment," states Neil Donaldson, VP of European Business Development. "We are pleased to see this segment of our market increase their interest in Provantis and believe there is opportunity for additional growth."

Siena Biotech has grown rapidly since 2000, when the Italian drug discovery company was founded, and has signed multiple international research & development collaborations and agreements. The company continues to expand both its high caliber scientific research staff and its research facilities.

Provantis is a modern, fully integrated Windows-based system for organizations and universities engaged in non-clinical evaluation studies. From single-user Pathologists to full-function global Toxicology/Pathology laboratories, Provantis™ streamlines processes and workflows with straightforward, intuitive functionality for simple and complex studies within a GLP or non-GLP environment.

About Instem

Instem is a world-leading information solutions provider for the Life Sciences - accelerating drug and chemical development by increasing client productivity and enhancing the processes that lead to safer, more effective products.

Instem's customer base consists of the leading pharmaceutical, chemical and contract research organizations, including government and privately funded programs across sites worldwide.

Established in 1969, Instem has offices in the United States and Europe with its solutions supported in fifteen countries. Instem serves large multi-national corporations and smaller organizations in overcoming the challenges of managing information and provides solutions that help them further their missions while creating a competitive advantage.

For more information on Instem and its solutions, please visit www.instem.com or contact them by email at info@instem.com.

Press Contact:

Gary E. Mitchell, VP Global Marketing, Instem US HQ
Tel: (610) 941-0990
Email: gary.mitchell@instem.com

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