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SOT Annual Meeting and ToxExpo

Virtual Booths at ToxExpo

Study Management Solutions

Instem preclinical solutions keep our clients focused on their science, not their software. Provantis®, the #1 online solution for managing preclinical studies. Come see our new “Insights” feature in our Pathology module. Learn about Submit™, the most widely adopted modular software suite for creating, reviewing, visualizing and managing SEND data. Our Genetic Tox Solutions are in a class of their own, featuring Comet Assay IV and Cyto Study Manager. Leading IT Solutions - Leading IT Results.

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SEND Solutions

Instem - the SEND experts. From study conversions to data verifications or consulting, we are the leading SEND authority. Our comprehensive services deliver exactly what our clients need, when they need it. Our intuitive submit™ software enables our DIY clients to create, QC review and visualize SEND datasets.

Our unmatched credentials enable organizations around the world to, submit™ with confidence.

Let us help SEND work for you.

Expertise. Speed. Quality.

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In Silico Tox Solutions

Instem’s In Silico Solutions suite of software and outsourced services enable researchers to generate new scientific insights through the identification, extraction and analysis of data to create actionable information.

KnowledgeScan™ Target Safety Assessment (TSA) Service: Delivering comprehensive TSAs for clients around the world, enabling them to make faster, better informed decisions on their drug targets.

Watch the KnowledgeScan Explainer video

Model Applier from Leadscope - an Instem Company: Advanced informatics and prediction technology, together with comprehensive database solutions that are helping organizations effectively unlock valuable knowledge contained in both public and proprietary sources of research data

Predict™ In Silico Toxicology service: A leading edge, technology-enabled service that delivers a combination of powerful computation models with expert scientific review, to help clients predict chemical safety more quickly, efficiently and comprehensively.

If you would like to schedule a discussion with us during SOT contact us at indicating your area of interest.

Instem Presentations

Please join us for an Exhibitor Hosted Presentation, no advance registration is required:

Leadscope - An Instem Company
Hot Topics in Computational Toxicology: New Developments that Support Regulatory Submissions

Monday, March 15
3:00pm - 4:00pm EST

This session considers how the latest developments in computational toxicology address critical regulatory and industrial use cases. We will discuss how N-Nitrosamine structure-activity relationships support carcinogenic potency categories, as well as how (Q)SAR models can be used for classification and labeling, the assessment of drug-drug interactions and skin sensitization.

Now Available On Demand

Today's SEND Challenges: How to Overcome Them and Realize Tomorrow's R&D Opportunities

Tuesday, March 16
9:00am - 10:00am EST

By working with customers from discovery through to regulatory approval we are uniquely positioned to see the reality and potential for SEND. We will review the common challenges of SEND, give practical advice on overcoming them, and then discuss the opportunities arising from the standardization of nonclinical data.

Now Available On Demand

Revolutionizing Target Safety Assessment: Technology Advancements and COVID-19 Target Case Study 

Wednesday, March 17
9:00am - 10:00am EST

In a pandemic-dominated year, coronavirus-related scientific publications escalated. Instem engaged big-data analytics to stay ahead of the data surge. Biological target safety remains immensely important to the pharmaceutical industry. Here, we demonstrate our R&D advancements, including innovative infographics and dynamic data visualizations, using the ACE2 receptor as an example target.

Now Available On Demand

Scientific Paper of the Year Award

We are delighted to announce that a scientific paper co-authored by Dr. Glenn Myatt, Instem’s Vice President of Informatics, has been awarded the Society of Toxicology (SOT) Computational Toxicology Speciality Section (CTSS) scientific paper of the year.

The open access paper, published in Regulatory Toxicology and Pharmacology, is titled “A cross-industry collaboration to assess if acute oral toxicity (Q)SAR models are fit-for-purpose for GHS classification and labelling”.

Dr. Myatt, along with a team of industry collaborators, assesses whether currently available acute oral toxicity (AOT) in silico models, provided by the widely employed Leadscope software, are fit-for-purpose for categorization and labelling of chemicals.


Dr. Myatt has been invited to accept the award on behalf of his co-contributors on Tuesday March 16th at the SOT-CTSS Virtual reception at the SOT’s upcoming Virtual 2021 Annual Meeting and ToxExpo.

The authors have generously donated the award money to support ongoing CTSS activities.

We are also pleased to be involved in the following poster:

Abstract Title: Predicting Acute Toxicity Using Computational Models

Presenting Author: Glenn Myatt

Session Title: Computational Toxicology II

Session Time: Tuesday, March 23 - 1:00pm to 2:45pm EST