From unveiling our fresh brand colors to reconnecting with industry leaders, SOT 2025 showcased our commitment to driving innovation in in silico toxicology.
A House Full of Engaged Attendees
Our scientific sessions and presentations were met with overwhelming interest, filling rooms with engaged professionals eager to explore the future of computational toxicology. We are proud to have sparked thought-provoking conversations that push the boundaries of predictive methodologies and toxicological risk assessment.
Spotlight on Our Scientific Presentations
We presented three groundbreaking papers.
1. Extraction of Knowledge from Proprietary Datasets for the Advancement of (Quantitative) Structure Activity Relationship Models
This session explored how proprietary data sources enhance in silico toxicology, driving more accurate and reliable safety assessments. Key topics included:
- The growth of in silico toxicology
- Why leveraging knowledge from proprietary datasets is crucial
- Knowledge integration techniques
- Strategies for extracting and utilizing proprietary data
- Case Study: Skin sensitization in silico models
2. Computational Toxicology to Support Safety Assessment of Extractables and Leachables (E&Ls)
This presentation addressed the complexities of E&L assessments, offering insights into strategies for managing data-poor compounds. Now available as on-demand webinar for those who couldn’t attend live.
Topics covered:
- Why E&Ls are important
- E&L toxicological risk assessment
- Understanding E&L structural classes
- Overcoming challenges associated with limited E&L data
- Defining a safer future in E&L risk assessment
3. Use of Read-Across in Different Scenarios: Lessons Learned and Best Practices Implementation
This presentation explored the role of read-across as a powerful methodology for assessing data-poor substances by leveraging robust experimental data from structurally and functionally similar analogs. Key discussion points included:
- The application of read-across in pharmaceuticals, industrial chemicals, consumer products, and food safety.
- Efforts by the read-across collaborative working group to establish standardized, cross-industry best practices.
- Integration of in silico models to enhance read-across justifications and weight-of-evidence approaches.
- Case studies demonstrating the practical application of read-across in regulatory and safety assessments.
By fostering regulatory acceptance and refining best practices, this work aims to create a harmonized, fit-for-purpose approach to read-across, supporting more reliable and scientifically sound safety assessments across industries.
A New Look, Same Commitment to Excellence
SOT 2025 also marked the unveiling of our updated brand colors, reinforcing our fresh approach and ongoing commitment to innovation in life science research.
Strengthening Industry Connections
The conference provided a fantastic opportunity to meet both new and familiar faces. From productive discussions with long-standing partners to engaging with fresh voices in the industry, SOT 2025 was a catalyst for collaboration and progress.
Access Our Presentation On-Demand
Missed our sessions? No problem! Our E&Ls presentation is now available as an on-demand webinar.
[Access the Webinars Now]
For those interested in learning more about Extraction of Knowledge from Proprietary Datasets for the Advancement of (Quantitative) Structure Activity Relationship Models and Use of Read-Across in Different Scenarios: Lessons Learned and Best Practices Implementation, we invite you to reach out to us at [email protected] to request a copy of the presentation.
In our upcoming blog posts, we will explore the key insights shared during these sessions, including how proprietary data can enhance in silico toxicology predictions, the latest advancements in read-across methodologies, and real-world case studies demonstrating best practices for regulatory acceptance. Stay tuned as we continue to share valuable knowledge on these critical topics.
We extend our gratitude to everyone who attended, engaged, and contributed to making SOT 2025 an unforgettable event. Let’s continue shaping the future of toxicology together!
