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      Accelerating R&D by delivering accurate predictions for wide-ranging toxicological endpoints, driven by regulatory guidelines.
      Predict
      Expert In Silico toxicology support delivering a wide range of reports with proven regulatory acceptance.
      KnowledgeScan
      Target safety assessment service for detailed insights into potential toxicological risks associated with drug targets.
      Centrus
      Advanced Translational Safety Solution enabling data alignment and review and visualizations.
      Advance
      Services delivering a detailed, expert-led S1B Weight of Evidence (WoE) assessment accelerating your development timeline.
      Key Insights from the Leadscope Consultants User Group Meeting
      Insights from the Leadscope Consultants User Group Meeting
      Leadscope’s Key Features Supporting Drug Discovery and Development.

      Read Now

      ClimbNEW
      Capture pre-clinical in vivo data from any therapeutic area into the cloud to accelerate studies.
      Provantis
      Market leading solution for preclinical GLP study management.
      Morphit
      Simplifies the process of capturing, analyzing, and reporting data for faster discovery research.
      Compliance BuilderNEW
      Audit trail and data integrity solution for scientific systems and files.
      Pristima
      Xybion Legacy study management software.
      BioRails
      Discovery solution optimizing bioanalysis workflows, accelerating in vitro ADME/DMPK studies and in vivo PK studies.
      Comet Assay IV
      Image analysis system for consistent and reliable comet assay scoring.
      Quality System Management (eQCM)NEW
      Electronic quality management system for regulatory compliance processes.
      Logbook
      Digitalization software enabling researchers to move away from paper-based systems.
      NOTOCORD-hem
      Software for advanced acquisition, analysis, and custom reporting of physiological signals.
      Cyto Study Manager
      Comprehensive Genetox assay management on one platform accelerating workflows and reducing costs.
      Kits ecommerce dropdown
      Climb’s Innovation Continues at Instem
      Advancing Non-GLP In Vivo Research with Speed, Flexibility, and Scientific Focus.

      Read Press Release

      SEND Advantage Services
      Services providing accelerated submission-ready SEND conversions, consultation, and verification.
      Submit
      Quickly create and manage high quality submission-ready SEND packages with a single suite of tools.
      SEND dataset 5-step blog
      A 5-Step SEND Dataset Checklist to Ensure Data Compliance
      It’s important to consider SEND guidelines throughout the process, not only before submission, to prevent costly surprises.

      Download Now

      Matrix Gemini LIMSNEW
      Configurable LIMS covering data collection, storage, and reporting while meeting global compliance and quality standards.
      choosing the right LIMS
      How to Select the Next Generation of Digital LIMS
      The Matrix Gemini LIMS white paper outlines four key considerations: performance, compliance, flexibility, and cost efficiency, to help laboratories choose the next generation of digital LIMS.

      Read Now

      Accel
      A turnkey, validated, and easy-to-use clinical analytics platform for all-sized biostats teams.
      Clinical Trial Transparency (CTT) Services
      Future-proof data and document sharing with de-identification and transparency strategizing services.
      Aspire
      Cloud-based SCE designed for large biostats teams looking to scale, automate, and future-proof workflows.
      Custom SCENEW
      A suite of services and technologies designed to build a tailored clinical analytics platform.
      Blur
      SaaS platform for de-identifying data and documents from clinical trials, removing risk and ensuring patient privacy.
      Kits ecommerce dropdown
      How to Build the Right SCE for Your Team
      This white paper explores the essential components of an effective SCE in clinical settings.

      Download Whitepaper

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      Toxicologists, Pathologists, and Safety Directors drive decisions with integrated tools and predictive insights.
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      Biostatisticians and Data Science Leads ensure valid, compliant analysis across preclinical and clinical studies.
      Study Leaders
      Study Directors and Program Managers coordinate study planning, execution, and reporting across disciplines.
      Kits ecommerce dropdown
      Matrix Gemini LIMS Fact Sheet
      Matrix Gemini LIMS delivers a flexible, configurable, and future-proof solution for laboratories of all sizes, helping users manage samples, data, and workflows efficiently while ensuring full regulatory compliance.

      Download Now

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      Watch on-demand sessions exploring emerging trends, product innovations, and best practices in life sciences R&D.
      Blog
      Read the latest blogs and gain industry insights from Instem’s deep bench of SMEs.
      White Papers
      In-depth analyses and technical papers providing guidance on regulatory compliance, data management, and research optimization.
      Provantis SRI case study
      Case Study: Provantis® Integrated Preclinical Software
      Download the case study to learn more about what challenges were overcome and what benefits were achieved with the deployment of Provantis.

      Download Now

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      Contact Us
      Get in touch with our team for product information, support, or partnership opportunities.
      Careers
      Explore opportunities to join Instem and help shape the future of research and discovery worldwide.
      Kits ecommerce dropdown
      Climb’s Innovation Continues at Instem
      Advancing Non-GLP In Vivo Research with Speed, Flexibility, and Scientific Focus.

      Read Now

  • Solutions NEW
    3 2
      In Silico & Data Insights
      Study Management
      Regulatory Submission
      Lab Execution
      Clinical Trial Analytics and Transparency
      Leadscope Model Applier
      Accelerating R&D by delivering accurate predictions for wide-ranging toxicological endpoints, driven by regulatory guidelines.
      Predict
      Expert In Silico toxicology support delivering a wide range of reports with proven regulatory acceptance.
      KnowledgeScan
      Target safety assessment service for detailed insights into potential toxicological risks associated with drug targets.
      Centrus
      Advanced Translational Safety Solution enabling data alignment and review and visualizations.
      Advance
      Services delivering a detailed, expert-led S1B Weight of Evidence (WoE) assessment accelerating your development timeline.
      Key Insights from the Leadscope Consultants User Group Meeting
      Insights from the Leadscope Consultants User Group Meeting
      Leadscope’s Key Features Supporting Drug Discovery and Development.

      Read Now

      ClimbNEW
      Capture pre-clinical in vivo data from any therapeutic area into the cloud to accelerate studies.
      Provantis
      Market leading solution for preclinical GLP study management.
      Morphit
      Simplifies the process of capturing, analyzing, and reporting data for faster discovery research.
      Compliance BuilderNEW
      Audit trail and data integrity solution for scientific systems and files.
      Pristima
      Xybion Legacy study management software.
      BioRails
      Discovery solution optimizing bioanalysis workflows, accelerating in vitro ADME/DMPK studies and in vivo PK studies.
      Comet Assay IV
      Image analysis system for consistent and reliable comet assay scoring.
      Quality System Management (eQCM)NEW
      Electronic quality management system for regulatory compliance processes.
      Logbook
      Digitalization software enabling researchers to move away from paper-based systems.
      NOTOCORD-hem
      Software for advanced acquisition, analysis, and custom reporting of physiological signals.
      Cyto Study Manager
      Comprehensive Genetox assay management on one platform accelerating workflows and reducing costs.
      Kits ecommerce dropdown
      Climb’s Innovation Continues at Instem
      Advancing Non-GLP In Vivo Research with Speed, Flexibility, and Scientific Focus.

      Read Press Release

      SEND Advantage Services
      Services providing accelerated submission-ready SEND conversions, consultation, and verification.
      Submit
      Quickly create and manage high quality submission-ready SEND packages with a single suite of tools.
      SEND dataset 5-step blog
      A 5-Step SEND Dataset Checklist to Ensure Data Compliance
      It’s important to consider SEND guidelines throughout the process, not only before submission, to prevent costly surprises.

      Download Now

      Matrix Gemini LIMSNEW
      Configurable LIMS covering data collection, storage, and reporting while meeting global compliance and quality standards.
      choosing the right LIMS
      How to Select the Next Generation of Digital LIMS
      The Matrix Gemini LIMS white paper outlines four key considerations: performance, compliance, flexibility, and cost efficiency, to help laboratories choose the next generation of digital LIMS.

      Read Now

      Accel
      A turnkey, validated, and easy-to-use clinical analytics platform for all-sized biostats teams.
      Clinical Trial Transparency (CTT) Services
      Future-proof data and document sharing with de-identification and transparency strategizing services.
      Aspire
      Cloud-based SCE designed for large biostats teams looking to scale, automate, and future-proof workflows.
      Custom SCENEW
      A suite of services and technologies designed to build a tailored clinical analytics platform.
      Blur
      SaaS platform for de-identifying data and documents from clinical trials, removing risk and ensuring patient privacy.
      Kits ecommerce dropdown
      How to Build the Right SCE for Your Team
      This white paper explores the essential components of an effective SCE in clinical settings.

      Download Whitepaper

  • Applications
    3 2
      By Role
      Lab Operations
      Lab Managers and Facility Supervisors rely on connected systems to streamline workflows and ensure compliance.
      Data Managers
      IT and Regulatory Leads safeguard data quality, submissions, and traceability across global research programs.
      Safety Professionals
      Toxicologists, Pathologists, and Safety Directors drive decisions with integrated tools and predictive insights.
      Biostats Professionals
      Biostatisticians and Data Science Leads ensure valid, compliant analysis across preclinical and clinical studies.
      Study Leaders
      Study Directors and Program Managers coordinate study planning, execution, and reporting across disciplines.
      Kits ecommerce dropdown
      Matrix Gemini LIMS Fact Sheet
      Matrix Gemini LIMS delivers a flexible, configurable, and future-proof solution for laboratories of all sizes, helping users manage samples, data, and workflows efficiently while ensuring full regulatory compliance.

      Download Now

  • Resources
    3 2
      Resources
      All Resources
      Check out the latest resources including whitepapers, flyers, webinars and more.
      Case Studies
      Discover how leading organizations are accelerating their research using Instem’s solutions and services.
      Fact Sheets
      Concise product summaries highlighting key features, benefits, and technical specifications.
      Webinars
      Watch on-demand sessions exploring emerging trends, product innovations, and best practices in life sciences R&D.
      Blog
      Read the latest blogs and gain industry insights from Instem’s deep bench of SMEs.
      White Papers
      In-depth analyses and technical papers providing guidance on regulatory compliance, data management, and research optimization.
      Provantis SRI case study
      Case Study: Provantis® Integrated Preclinical Software
      Download the case study to learn more about what challenges were overcome and what benefits were achieved with the deployment of Provantis.

      Download Now

  • Company
    3 2
      Company
      About Us
      Learn more about Instem’s history, culture, and mission to enable smarter, faster decisions in life sciences R&D.
      Events
      Meet the team at upcoming conferences and industry gatherings around the world.
      Leadership Team
      Meet the leaders guiding Instem’s strategy and driving innovation across our global organization.
      Company News
      Stay up to date with the latest announcements, product releases, and corporate developments from Instem.
      Contact Us
      Get in touch with our team for product information, support, or partnership opportunities.
      Careers
      Explore opportunities to join Instem and help shape the future of research and discovery worldwide.
      Kits ecommerce dropdown
      Climb’s Innovation Continues at Instem
      Advancing Non-GLP In Vivo Research with Speed, Flexibility, and Scientific Focus.

      Read Now

Contact Us
Book a Demo
  • Solutions
    • In Silico & Data Insights
      • Leadscope Model Applier
      • Knowledgescan
      • Advance
      • Predict
      • Centrus
    • Study Management
      • Climb
      • Pristima
      • Logbook
      • Provantis
      • Biorails
      • NOTOCORD-hem
      • Morphit
      • Comet Assay IV
      • Cyto Study Manager
      • Compliance Builder
      • Quality System Management (eQCM)
    • Regulatory Submission
      • SEND Advantage Services
      • Submit
    • Lab Execution
      • Matrix Gemini LIMS
    • Clinical Trial Analytics and Transparency
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Insights from the Leadscope Consultants User Group Meeting

Insights from the Leadscope Consultants User Group Meeting

by Candice Johnson, PhD | Oct 9, 2025 | In Silico Insider

The recent Leadscope Consultants User Group Meeting brought together Leadscope’s scientists and industry consultants to explore how Leadscope’s in silico tools are supporting drug discovery and development. The session, which was hosted by Candice Johnson (Product...
International Collaboration on Cosmetic Safety: Skin Sensitization Assessment Using NAMs

International Collaboration on Cosmetic Safety: Skin Sensitization Assessment Using NAMs

by Candice Johnson, PhD | Sep 11, 2025 | In Silico Insider

The International Collaboration on Cosmetic Safety (ICCS) recently published its Best Practice Guidance (BPG) Document for skin sensitization assessment using New Approach Methods (NAMs) for substances in cosmetics and personal care products1. This BPG...
Advancing Chemical Safety: An In Silico Protocol for Endocrine Activity Assessment 

Advancing Chemical Safety: An In Silico Protocol for Endocrine Activity Assessment 

by Candice Johnson, PhD | Aug 7, 2025 | In Silico Insider

In the evolving landscape of chemical safety and regulatory science, the assessment of endocrine-disrupting chemicals (EDCs) has become a critical priority.  Endocrine disruption (ED) has been introduced as a classification and labelling category in Regulation (EC) No...
ICH M7: From Guideline to Practical Workflow 

ICH M7: From Guideline to Practical Workflow 

by Candice Johnson, PhD | Jul 17, 2025 | In Silico Insider

This blog explores how protocol-driven (Q)SAR assessments became routine in ICH M7-based impurity evaluations.  How ICH M7 Is Applied: Practical Steps for (Q)SAR Mutagenicity Assessment  It has been 9 years since the publication of the Principles and Procedures...
Significance of Chemical Grouping in E&L Risk Assessment 

Significance of Chemical Grouping in E&L Risk Assessment 

by Candice Johnson, PhD | Jun 5, 2025 | In Silico Insider

Excerpt from our presentation titled Applications of Chemical Grouping in Extractables and Leachables (E&L) Risk Assessments at Extractables & Leachables US 2025. In toxicology, chemical grouping supported by clustering approaches offers a science-based...
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Life Science Software – Drug Research & Development
  • Solutions
    • In Silico & Data Insights
      • Leadscope Model Applier
      • Knowledgescan
      • Advance
      • Predict
      • Centrus
    • Study Management
      • Climb
      • Pristima
      • Logbook
      • Provantis
      • Biorails
      • NOTOCORD-hem
      • Morphit
      • Comet Assay IV
      • Cyto Study Manager
      • Compliance Builder
      • Quality System Management (eQCM)
    • Regulatory Submission
      • SEND Advantage Services
      • Submit
    • Lab Execution
      • Matrix Gemini LIMS
    • Clinical Trial Analytics and Transparency
      • Accel
      • Aspire
      • Blur
      • Clinical Trial Transparency (CTT) Services
      • Custom SCE
  • Applications
    • By Role
      • Lab Operations
      • Safety Professionals
      • Study Leaders
      • Data Managers
      • Biostatistics Professionals
  • Resources
    • All Resources
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    • Blog
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