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BioRails® Modules

BioHub™: Consolidate corporate knowledge into a single, accessible store, ensuring organized and readily available information.

BioRails PTO™: Enhance project tracking and optimization with tools for streamlined and precise project management.

BioRails DM™: Simplify data management with tools that ensure consistency and reliability in research data.

BioRails MT™: Register and manage biospecimens, biologics, and formulations with seamless tracking and utilization of materials.

BioRails INV™: Optimize inventory control with efficient systems for ordering and tracking resources.

BioRails InLife™: Boost productivity in the vivarium with tools for streamlined treatment and harvesting tasks.

Features for Security and Efficiency:
Created by Scientists for Scientists

Role-based Security Model: Implement a robust security model with differentiated access rights for enhanced protection.

Authorization and Authentication: Ensure data protection with strong authorization and authentication mechanisms.

Team and Project Support: Enable seamless project tracking and information sharing with support for teams and real-time collaboration.

Terms and Terminology Support: Manage pharmaceutical research data with chemically aware terminology support.

Quantity Model (Unit Handling): Handle various units of measurement with precision and scalability.

Content Management: Audit-friendly content management that tracks information accurately, consolidates data, and provides rich visualization and integrated tools.

Streamline Workflows: Automate complex workflows to ensure process consistency and scalability. Handle large data volumes uniformly, maintaining quality and integrity while reducing workload and errors.

Automate Data Collection: Minimize manual effort and reduce human error in data collection with automation tools. Free up time for critical activities by automating repetitive tasks.

BioRails® supports both structured experimentation and the integration of unstructured results into a structured environment. It empowers scientists with efficient data exploitation through advanced reporting and analysis tools, reducing the time needed to analyze data and draw conclusions.

BioRails®

BioHub™

BioHub™ Scalable Data Solution

Data loading and storing all assay results in a single database for ready decision-making.

Unified Data Repository

BioHub™ serves as a comprehensive data store, consolidating data from various sources into one centralized location. This eliminates the inefficiencies of fragmented data storage and provides a single point of access for all your data needs.

Robust Data Loading Mechanisms

BioHub™ supports diverse data loading methods, enabling seamless integration for both external CROs and internal teams. This ensures efficient data posting and minimizes the risk of data silos.

Rigorous Data Validation

All incoming data is meticulously validated against corporate standards and ontologies. BioHub™ ensures only high-quality, compliant data is published to the corporate data warehouse, maintaining data integrity and reliability.

Versatile Deployment Options

BioHub™ offers flexible deployment solutions, either in the cloud or on-premise. This adaptability allows organizations to choose the setup that best fits their infrastructure and security requirements.

Assay Registration and Results Upload

BioHub™ supports the registration of assays based on formally managed terminology and ontologies. Its user-friendly web interface facilitates the uploading of results from a wide range of assays, from high-throughput screening (HTS) to complex in vitro and in vivo assays.

Integration with Leading Analytics Tools

BioHub™ integrates seamlessly with top HTS data analytics software, enabling large datasets to be published directly. This integration reduces the time and errors associated with manual file manipulations.

Secure Access for CROs

BioHub™ provides secure access for Contract Research Organizations (CROs) to upload and exchange results. This secure sharing capability enhances collaboration and data exchange efficiency.

Scalability for Growing Organizations

Combined with BioRails Warehouse, BioHub™ scales effortlessly to meet the needs of organizations of any size. It can absorb data from numerous sources, creating a robust and scalable resource of results.

Compatibility with Advanced Informatics Tools

The data stored in BioHub™ can be easily accessed and utilized by most scientific data informatics tools. This compatibility provides an ideal foundation for data scientists to develop AI algorithms based on corporate knowledge.

BioHub™ revolutionizes data management by providing a scalable, centralized, and compliant data store. Its robust data loading mechanisms, rigorous validation processes, and flexible deployment options make it the ideal solution for organizations looking to enhance their data consolidation and analysis capabilities. With seamless integration into leading analytics tools and secure access for CROs, BioHub™ ensures that high-quality data is always at your fingertips, empowering data-driven decision-making, and innovation.

BioRails PTO™

BioRails PTO™ Project Tracking and Optimization

A service request and planning tool that enhances discovery research by streamlining assay workflows, improving collaboration, and reducing cycle times.

Service Definition

BioRails PTO™ allows you to define a variety of services that can be requested, ensuring all necessary details are captured. These services can represent assays, studies, or general services and are based on item types such as compounds, batches, animals, or instruments. This detailed service definition ensures that requesters have all the information they need to accurately specify their requirements.

Assay Requesting

Project teams can easily submit assay requests for published services using BioRails PTO™. This streamlined requesting process ensures that all requests are comprehensive and consistent, reducing errors and facilitating efficient project execution.

Planning and Scheduling

Submitted assay requests are consolidated into organized 'Todo lists', allowing planners to allocate items into execution units such as runs, experiments, or studies. BioRails PTO™ provides tools for scheduling start times and allocating personnel, ensuring optimal resource utilization and project timelines.

Inventory Integration

When integrated with BioRails INV, planners can evaluate stock levels while requesting assays. This integration allows them to request assay-ready plates from compound management teams, ensuring that all necessary materials are available for seamless execution.

Cascade

BioRails PTO™ enables the definition of cascades of assays, organized into multiple tiers. Each tier generates results that can be automatically evaluated using predefined rules to promote compounds to the next level of assays. This feature allows you to track and monitor progress efficiently, reducing cycle times and accelerating the time to market for new treatments.

BioRails PTO™ offers a comprehensive suite of tools for assay requesting, planning, and cascading. Its intuitive interface and automated features streamline workflows, enhance collaboration, and ensure high-quality results. Whether you're a scientist requesting assays or a service provider managing multiple projects, BioRails PTO™ provides the precision and efficiency needed to drive your discovery research forward, reducing cycle times and bringing innovative treatments to market faster.

BioRails DM™

BioRails DM™ Advanced Data Management Solutions

A data management solution that streamlines data capture, processing, and analysis through a workflow-driven approach, integrating advanced analytics and reporting to transform raw data into actionable insights.

Structured Data Management

BioRails DM™ provides an effective platform for comprehensive data management, enabling organizations to implement the highest standards in the field. It supports both structured data capture (results) and unstructured data (observations and interpretations), ensuring all aspects of your data are managed efficiently. Define experimental workflows that combine data capture processes with structured data storage and powerful data analytics templates using Morphit.

Workflow-Driven Coordination

BioRails DM™ coordinates activities across multiple departments, internally and with partners and CROs. It enables the definition and execution of high-level workflows addressing various data types captured during scientific experiments. The platform uses analytical templates to drive laboratory workflows, generating plate maps, injection lists for Mass Spectrometers, robotics instruction files, and other experimental artifacts. It reads and analyzes instrument files from fluorescence readers, Mass Spectrometers, and many other types of instruments.

Knowledge Capture and Protection

Avoid the need to print data into PDFs and protect your knowledge efficiently. BioRails DM™ includes a 21 CFR Part 11 compliant notebook for writing up experiments, complete with electronic signatures and witnessing. This ensures your data is securely captured and easily retrievable for future reference.

Advanced Analytics

Apply statistics, curve fitting, and other analytical techniques to transform raw data into meaningful results. BioRails DM™ allows for the application of advanced quality control criteria within and across experiments to ensure data quality. Search and analyze results across studies to extract valuable knowledge and understanding.

Documentation and Reporting

Create documentation templates for study reports, quality reports, certificates of analysis, and various other types of reports. BioRails DM™ allows you to generate high-quality documentation at the press of a button, combining data, results, charts, graphs, and images from within or across experiments. This feature saves hours of time in compiling and formulating documentation.

Electronic Signatures and Compliance

BioRails DM™ supports electronic signatures and witnessing as part of its CFR 21P11 compliance effort. This ensures that all data and processes meet regulatory standards, providing peace of mind and reliability.

Bulk Data Loading

Load results from CROs and internal teams using bulk loading tools, building extensive databases with hundreds of millions of results. This capability supports the efficient management of large datasets, essential for high-throughput environments.

Industry Focus

While BioRails DM™ can address many data capture processes, it is particularly focused on the following areas:

  • In vitro Drug Metabolism
  • In vivo Pharmacokinetics
  • Bioanalysis
  • In vitro Pharmacology (Screening)

Integration and Compatibility

BioRails DM™ includes Morphit and is compatible with InLife, ensuring seamless integration with existing systems and enhancing overall functionality.

BioRails DM™ is a robust data management solution that transforms how organizations handle data capture, processing, and analysis. Its workflow-driven approach ensures data, processes, and insights are secured and managed in one place, promoting efficiency and compliance. By integrating advanced analytics, secure data capture, and comprehensive reporting, BioRails DM™ transforms raw data into actionable insights, driving informed decision-making and accelerating research and development.

BioRails MT™

BioRails MT™ Comprehensive Material Tracking and Management

A material tracking and management solution supporting the registration of test articles, controls, standards, and assay reagents.

Material Registration

BioRails MT™ is designed to support organizations conducting a wide variety of research and development activities. While traditional systems manage specific entities like compounds, lots, proteins, and antibodies, BioRails MT™ extends this capability to a broader range of materials. It integrates with existing compound and biological registration systems, supporting the entire Request-Plan-Test cycle. This includes materials generated during in vivo studies, such as plasma, blood, tissues, and formulation samples, which are often not formally managed by other systems.

Comprehensive Material Management

With BioRails MT™, organizations can register and manage various materials, tracking their properties and leveraging the BioRails Request-Plan-Test workflow. This system also keeps track of the quantity and location of samples, ensuring that all materials are accounted for and easily accessible when needed.

Support for Contract Research Organizations (CROs)

CROs often receive samples from multiple customers worldwide, typically accompanied by high-level information like IDs and basic properties. BioRails MT™ allows CROs to register these samples, manage the delivery of testing services, and handle both fee-for-service work and integrated projects. CROs can manage the distribution of samples for testing across multiple sites. This transparency improves efficiency, reduces turnaround times, and enables the delivery of more services with the same resources.

BioRails MT™ offers a robust solution for comprehensive material tracking and management, enhancing operational efficiency and precision in inventory control. The flexibility and integration capability make it an indispensable tool for organizations and CROs looking to optimize their workflows and ensure the accuracy and availability of their materials.

BioRails INV™

BioRails INV™ Efficient Inventory Control and Supply Management

Comprehensive Inventory Management

BioRails INV™ offers a comprehensive inventory system designed to support various operations, including in-house, externalized, and hybrid setups. It efficiently manages sample inventory across different locations, including sites, labs, fridges, and freezers. Containers such as microtiter plates, racks, and vials are registered and tracked with precision, ensuring accurate inventory control.

Flexible Container Support

The system supports both automated tube stores and traditional stores, catering to diverse storage needs. Whether it's automated storage solutions or conventional storage methods, BioRails INV™ seamlessly manages containers to meet the requirements of different laboratories and research facilities.

Plate Preparation

BioRails INV™ facilitates efficient plate preparation processes, including dilutions, stamps, and quad-mapping. This feature streamlines the preparation of assay-ready plates, reducing turnaround time and ensuring that project teams receive results faster. Whether handling solids or liquids, small or large molecules, BioRails INV™ ensures accurate and efficient plate preparation for various experiments.

Stock Ordering and Receipt Operations

Users can easily search current inventory stocks for powders or liquid samples and identify samples that fulfill assay needs. BioRails INV™ enables quick and efficient ordering operations, allowing users to place orders for sample delivery seamlessly. The system also supports tracking dispatch and receipt of samples from CROs, ensuring smooth logistics operations.

Stock Reconciliation

BioRails INV™ facilitates stock reconciliation operations, helping users reconcile stock differences efficiently. This feature ensures data accuracy and integrity, enabling users to maintain precise inventory records and minimize discrepancies.

BioRails INV™ offers a powerful solution for managing sample inventory efficiently and effectively. With its comprehensive features for container tracking, plate preparation, stock ordering, and reconciliation, BioRails INV™ streamlines inventory management processes, enhances operational efficiency, and accelerates research workflows. Whether it's managing containers across different locations or preparing assay-ready plates, BioRails INV™ provides the flexibility and precision needed to optimize inventory control and supply management in pharmaceutical and biopharmaceutical companies.

Workflow Solutions

BioRails® Workflow Solutions

To meet the dynamic needs of the drug discovery space, our solutions are designed to enhance efficiency, reliability, and flexibility in your research processes. These workflow solutions deliver optimized assay planning and execution within BioRails and Morphit, accelerating deployment and ensuring best practices are adopted.

Features of BioRails Workflow Solutions

Clear: Our workflows come fully documented, ensuring that every step is transparent and easy to follow. 

Ease of Use: With instruction-driven designs, our solutions are user-friendly, enabling seamless adoption by your team. 

Reliable: Each workflow is scientifically validated to provide consistent and accurate results. 

Straightforward: Consistent design principles make our workflows intuitive, reducing the learning curve for your team. 

Versatile: Our solutions easily adapt to different instruments and experimental setups, providing unparalleled flexibility. 

Flexible Integration: Whether you need a standalone solution or something that integrates seamlessly with existing systems, our workflows are designed to fit your needs. 

Comprehensive Assay Support:
A wide range of assays critical to drug discovery, including but not limited to:

  • LogD
  • Solubility
  • BBB (Blood-Brain Barrier)
  • Partitioning
  • Permeability
  • Stability
  • Clearance
  • Binding
  • Enzyme Inhibition and Activation

Advanced Assay Planning:
Robust assay planning capabilities, ensuring that your experiments are not only executed efficiently but also strategically planned for optimal outcomes.

  • Prep Assay & Analysis plates (robotic worklists)
  • Pre and post-Assay cassette support
  • Generate batch files for MS

BioRails Workflow Solutions

In Vitro DMPK

In Vitro Pharmacology

In Vivo PK

Bioanalysis

BioRails Workflow Solutions: Bridging Innovation and Application in Drug Discovery