Predict™
Accelerate Toxicology Studies With Confidence and Clarity
Predict is an in silico toxicology service for robust chemical safety assessments. This service leverages human expertise, powerful computational models, and data from over 600,000 studies to deliver accurate, regulator-ready reports, allowing researchers to make better informed decisions and accelerate development with confidence.
Ready to make smarter, faster, and safer decisions? Request your Predict demo today.
What is Predict?
Predict is a leading computational toxicology service integrating advanced predictive technology with defendable expert review to simplify and strengthen chemical safety assessments. By drawing on a curated database of over 600,000 studies covering more than 200,000 chemicals, Predict reduces the need for manual literature reviews, which can be time-consuming and leave critical gaps.
Our transparent, expert-led approach ensures assessments are always up to date, accurate, and regulator-ready, offering a level of reliability and efficiency that traditional methods can’t match. Predict is fully scalable to client needs and offers fast turnaround times without sacrificing accuracy. Furthermore, Instem provides expertise in regulatory requirements and guidelines, ensuring that your project is set up for success.
You can be confident that your assessments meet the highest standards and will be accepted by key regulatory agencies worldwide.
Key Benefits of Predict
Enhances Regulatory Compliance
Predict is geared towards global regulatory guidelines, ensuring compliance with ICH M7 and Q3A/B/C standards, among many others.
Speeds Development
Ensures Cost-efficiency
Provides Actionable Insights
Removes Risk
Core Features
Mutagenicity (Q)SAR Assessment
N-nitrosamines Levels
Evaluates the potential toxicological risk of N-nitrosamines, helping researchers establish acceptable limits and support safety documentation in line with regulatory guidance on pharmaceutical impurities.
Extractables and Leachables
Derives Permitted Daily Exposure (PDE) values for extractables and leachables, ensuring best practices and rigorous methodologies are followed to communicate safety levels and combining read-across strategies based on suitable analogues for data-poor substances.
Non-mutagenic impurities
Assesses and communicates safe levels on non-mutagenic impurities based on available data and a read-across strategy for data poor-substances that evaluates toxicophores.
SD File Generation
Clients receive ready-to-use SD files for seamless integration into Electronic Common Technical Document (eCTD) submissions.
Comprehensive (Q)SAR Assessment
Delivers an in-depth full toxicological profile across carcinogenicity, mutagenicity, reproductive/developmental toxicity, endocrine activity, acute oral toxicity, skin sensitization, irritation/corrosion, organ toxicity, bioactivation, and abuse liability endpoints. This gives researchers a comprehensive view of potential risks, enabling faster, more informed decisions.
Bespoke (Q)SAR Assessment
Provides customizable evaluations focused on specific endpoints and is tailored to address specific guidelines, ensuring researchers only pay for the insights they need.
Why Choose Predict?
Predict delivers toxicology assessments that are faster, more comprehensive, and more flexible than traditional workflows. Unlike other solutions, Predict gives researchers access to Instem’s database of over 600,000 toxicity studies covering 200,000+ chemicals, addressing all major endpoints. This ensures assessments are built on current and robust data. Each report is reviewed by domain experts, guaranteeing that it is regulator-ready while providing transparency to help guide next steps.
Whether working with limited internal resources or facing tight regulatory timelines, Predict ensures you move forward with clarity, confidence, and scientific rigor.
How It Works
Predict leverages Instem’s expertise in delivering technology-enabled services, powered by advanced informatics and prediction technology, and comprehensive database solutions.
Initial Alignment
Data Identification
We leverage our extensive 600,000-study database to identify relevant toxicology data and generate SD files for our clients.
In Silico Analysis
Our team uses world-leading computational models to provide accurate and unbiased chemical safety assessments.
Expert Review
Domain experts review the data to ensure scientific accuracy, regulatory compliance, and clear, actionable conclusions.
Flexible Service Options
Clients can choose the streamlined “Core” service for fast results or the “Full” service for comprehensive, expert-reviewed reports.
Frequently Asked Questions
Predict supports a wide range of applications, each with its specific requirements. Here are some of the most common questions we receive about its use.
Does Predict integrate easily with our submission workflows?
Yes, the Predict service provides a transparent report that addresses the objectives defined in the project scope. This report could be used either for internal decision making or for regulatory submissions.
Is Predict suitable for small organizations or startups?
Yes, Predict is fully scalable, making it an excellent choice for smaller organizations looking to optimize their resource allocation. Likewise, larger organizations would also value the expert insight and flexibility to outsource projects as needed.
Can we choose which toxicity endpoints to assess?
Absolutely. Predict offers both standard and bespoke (Q)SAR assessments, allowing you to focus only on the endpoints relevant to your project.
Is training required to use Predict?
No training is needed. Predict is a service, not a platform. Our experts listen to your needs, handle the technical work and deliver clear, ready-to-use results.
Get a Free Demo Today
Eliminate uncertainty and make informed decisions with expert-reviewed toxicology insights and advanced predictive models. Want to streamline toxicology assessments and boost regulatory confidence with a faster, more reliable approach?