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Advancing Risk-Based E&L Safety Assessment: The Role of ICH Q3E and Leadscope

Jignyasa Bal

June 24, 2026

As ICH Q3E advances a risk-based paradigm for E&L safety, the question is shifting from whether to assess risk toward how to do it consistently across a vast and diverse chemical space. Leadscope enables structure...

CRODiscoveryIn Silico & Data InsightsIn Silico InsiderLeadscopeLeadscope Model ApplierPharmaceuticalPre-ClinicalPredictive ToxicologyPress ReleasesToxicology

Leadscope Model Applier™ v2026 – Expanding confidence in predictive toxicology

Jignyasa Bal

April 28, 2026

This release introduces advanced predictive models and extensive toxicological data to support rigorous chemical safety assessments.

BiotechCRODiscoveryIn Silico InsiderKnowledgeScanLeadscope Model ApplierPharmaceuticalPre-ClinicalPredictive ToxicologyToxicology

Preparing Future Leaders in Computational Toxicology: A Scientific Perspective

Candice Johnson, PhD

January 22, 2026

My colleague Frances Hall and I had the privilege of publishing an article titled “Bridging science and curriculum: preparing future leaders in computational toxicology”

AgencyBiotechCRODiscoveryDrug DiscoveryIn Silico InsiderLeadscope Model ApplierPharmaceuticalPre-ClinicalPredictPredictive Toxicology

In Silico Insights in Preclinical Research and Development

Candice Johnson, PhD

December 11, 2025

How data insights and in silico technologies can enable decision-making

BiotechCRODiscoveryDrug DiscoveryIn Silico InsiderLeadscope Model ApplierPharmaceuticalPredictive Toxicology

Insights from the Leadscope Consultants User Group Meeting

Candice Johnson, PhD

October 9, 2025

Leadscope’s Key Features Supporting Drug Discovery and Development

BiotechDiscoveryIn Silico InsiderLeadscope Model ApplierPharmaceuticalPre-ClinicalToxicology

International Collaboration on Cosmetic Safety: Skin Sensitization Assessment Using NAMs

Candice Johnson, PhD

September 11, 2025

A review on the recently published ICCS Best Practice Guidance Document for skin sensitization assessment using New Approach Methods (NAMs)

In Silico Insider Blog

Advancing Risk-Based E&L Safety Assessment: The Role of ICH Q3E and Leadscope

Leadscope Model Applier™ v2026 – Expanding confidence in predictive toxicology

Preparing Future Leaders in Computational Toxicology: A Scientific Perspective

In Silico Insights in Preclinical Research and Development

Insights from the Leadscope Consultants User Group Meeting

International Collaboration on Cosmetic Safety: Skin Sensitization Assessment Using NAMs

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