NOTOCORD‑hem 5.3 builds on the established NOTOCORD‑hem software, introducing new analytical modules and performance improvements to support advanced physiological research. The platform continues to provide a comprehensive environment for the acquisition, analysis, and reporting of physiological data across cardiovascular, respiratory, and nervous system applications.
Designed for nonclinical and academic research, NOTOCORD‑hem enables the analysis of data from multiple experimental conditions, including in vivo, in vitro, and ex vivo studies, across various animal species.
Solution Overview
NOTOCORD‑hem is a software platform that allows researchers to:
• Acquire and analyze physiological signals using a modular architecture
• Utilize over 160 specialized modules for customized workflows
• Generate configurable reports directly from acquired data
• Conduct studies across conscious and anesthetized animal models
• Integrate data from implantable systems, organ baths, and patch clamp setups.
New Capabilities in Version 5.3
Version 5.3 introduces three new modules that enhance analytical depth, particularly in sleep research, while improving signal processing and system performance.
Sleep Analysis Modules
SLP30a – Sleep Analyzer for Small Animals
• Automated classification of sleep stages (Wake, NREM, REM)
• Analysis of EEG, EMG, and activity signals
• Generation of complete hypnograms
• Support for real‑time and post‑acquisition analysis
• Outputs including spectral analysis, sleep architecture metrics, and signal quality control
This module enables efficient evaluation of sleep patterns and the assessment of central nervous system function.
RME11h – Reference Mark Editor for Sleep
• Manual review and editing of automatically classified sleep stages
• Intuitive navigation for hypnogram refinement
• Optional synchronization with video data
• Full traceability to support regulated workflows
This module ensures reliable validation of analysis results while maintaining compliance requirements.
Advanced Signal Processing
ITP40a – Interpolation Filter Module
• Reconstruction of missing signal samples
• Resampling and harmonization of multi‑device data
• Support for interpolation methods, including step, linear, and spline
This module improves signal consistency and supports enhanced downstream analytical accuracy.
Reporting Enhancements
Excel Wizard Improvements
• Improved visualization of overlapping data using minimum/maximum envelopes
• Introduction of an “Evaluate” function for real‑time validation of formulas
• Enhanced navigation, zooming, and extraction zone behavior
• Increased accuracy and stability in data extraction processes
Performance and Stability Improvements
• STE20 series: Improved handling of signal gaps to prevent system instability
• LVP31/LVP32: Optimized memory allocation for enhanced computational performance
• Increased robustness across analytical workflows
Conclusion
NOTOCORD‑hem 5.3 extends the capabilities of an established physiological data analysis platform by introducing validated workflows for sleep analysis, improved signal processing techniques, and enhanced reporting and system performance. The platform continues to support rigorous scientific research with reliability, flexibility, and compliance.
Schedule a demonstration to evaluate how NOTOCORD‑hem 5.3 can support advanced physiological data analysis workflows.
