In Silico Presentations

Please click on a link below to watch one of our strategic In Silico presentations

Implementation of a Weight of Evidence Carcinogenicity Assessment Aligned with ICH S1B

This presentation reviews the state-of-the-art in assessing carcinogenicity based on the ICH S1B weight of evidence (WoE) addendum, including progress towards developing a transparent and defendable protocol based on the 6 WoE factors.

Presented by Glenn Myatt, PhD, SVP of In Silico & Translational Science Solutions, Instem, Arianna Bassan, Principal Consultant, Innovatune and Frances Hall, PhD, Senior Director, In Silico Solutions, Instem

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Assessing N-nitrosamine Potency Classes

This presentation reviews recent regulatory and industry updates in the assessment of N-nitrosamine potency classes based on various collaborations. It outlines new defendable methods, including SAR and read-across approaches, based on a mechanistic understanding of N-nitrosamine carcinogenicity.  

Presented by Kevin Cross, PhD, VP of Product Development, Instem & Arianna Bassan, Principal Consultant, Innovatune

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