Understand how applicability domain affects QSAR prediction confidence and why chemical coverage matters when assessing pharmaceutical impurities under ICH M7.
Mutagenicity assessment is the critical first step in pharmaceutical impurity risk evaluation, and this blog explores the scientific principles underpinning robust ICH M7 assessments, from complementary QSAR methodologies and Ames study data to applicability domain...
CMC readiness begins long before IND submission. Explore how early data-driven decision-making, predictive toxicology, and connected workflows can reduce risk, improve data quality, and simplify regulatory preparation throughout the drug development journey.
As ICH Q3E advances a risk-based paradigm for E&L safety, the question is shifting from whether to assess risk toward how to do it consistently across a vast and diverse chemical space. Leadscope enables structure...
This release introduces advanced predictive models and extensive toxicological data to support rigorous chemical safety assessments.
Instem, a leading provider of SaaS solutions for preclinical R&D, today announced the appointment of Szczepan Baran, VMD, MS, as Chief Scientific Officer. In the role, Szczepan will lead scientific and AI strategy across in...
